SOX8 antibody (AA 101-200) (Biotin)

Catalog No. ABIN1392235

Product Details anti-SOX8 Antibody (Biotin)

Target: SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

Binding Specificity: AA 101-200

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX8 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SOX8

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SOX8

Target: SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

Alternative Name: SOX8 (SOX8 Products)

Synonyms: SRY-box 8 antibody, SRY box 8 antibody, SRY-box 8 L homeolog antibody, SRY (sex determining region Y)-box 8 antibody, SOX8 antibody, Sox8 antibody, sox8.L antibody

Background:

Synonyms: SOX 8, Sox8, SOX8_HUMAN, SRY sex determining region Y box 8, SRY box 8, SRY box containing gene 8, Transcription factor SOX 8, Transcription factor SOX-8, Transcription factor SOX8.

Background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Pathways: Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development