SOX13 antibody (AA 401-500) (Biotin)

Catalog No. ABIN1392151

Product Details anti-SOX13 Antibody (Biotin)

Target: SOX13 (SRY (Sex Determining Region Y)-Box 13 (SOX13))

Binding Specificity: AA 401-500

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX13 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ICA12

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SOX13

Target: SOX13 (SRY (Sex Determining Region Y)-Box 13 (SOX13))

Alternative Name: ICA12/SOX13 (SOX13 Products)

Synonyms: ICA12 antibody, Sox-13 antibody, AA407916 antibody, AW259412 antibody, AW540933 antibody, SRY-box 13 antibody, SRY (sex determining region Y)-box 13 antibody, SRY box 13 antibody, SOX13 antibody, Sox13 antibody

Background:

Synonyms: ICA 12, ICA12, Islet cell antibody 12, Islet cell antigen 12, MGC117216, SOX 13, SOX 13 protein, sox13, SOX13 protein, SOX13_HUMAN, SRY Sex determining region Y-box 13, SRY box 13, SRY box containing gene 13, SRY related HMG box gene 13, SRY sex determining region Y box 13, Transcription factor SOX 13, Transcription factor Sox-13, Type 1 diabetes autoantigen, Type 1 diabetes autoantigen ICA 12, Type 1 diabetes autoantigen ICA12.

Background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.