FOXD3 antibody (AA 151-230) (Biotin)

Catalog No. ABIN1391743

Product Details anti-FOXD3 Antibody (Biotin)

Target: FOXD3 (Forkhead Box D3 (FOXD3))

Binding Specificity: AA 151-230

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXD3 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FOXD3

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FOXD3

Target: FOXD3 (Forkhead Box D3 (FOXD3))

Alternative Name: FOXD3 (FOXD3 Products)

Synonyms: AIS1 antibody, Genesis antibody, HFH2 antibody, VAMAS2 antibody, CWH3 antibody, Hfh2 antibody, fkd6 antibody, fkh6 antibody, forkhead-6 antibody, zgc:111934 antibody, XFD-6 antibody, xfoxd3 antibody, FOXD3 antibody, genesis antibody, hfh2 antibody, foxd3b antibody, foxd3b-A antibody, forkhead box D3 antibody, forkhead box D3 L homeolog antibody, forkhead box D3 S homeolog antibody, FOXD3 antibody, Foxd3 antibody, foxd3 antibody, foxd3.L antibody, foxd3.S antibody

Background:

Synonyms: Forkhead box protein D3, HNF3/FH transcription factor genesis, HFH2

Background: This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. Mutations in this gene cause autoimmune susceptibility 1. Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.

Gene ID: 27022

UniProt: Q9UJU5