BBS9 antibody (AA 244-320) (AbBy Fluor® 350)
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- Target See all BBS9 Antibodies
- BBS9 (Bardet-Biedl Syndrome 9 (BBS9))
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Binding Specificity
- AA 244-320
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BBS9 antibody is conjugated to AbBy Fluor® 350
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse,Dog,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human BBS9
- Isotype
- IgG
- Top Product
- Discover our top product BBS9 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- BBS9 (Bardet-Biedl Syndrome 9 (BBS9))
- Alternative Name
- BBS9 (BBS9 Products)
- Synonyms
- b1 antibody, B1 antibody, C18 antibody, D1 antibody, PTHB1 antibody, RGD1308472 antibody, E130103I17Rik antibody, Bardet-Biedl syndrome 9 antibody, bardet-biedl syndrome 9 antibody, Bardet-Biedl syndrome 9 (human) antibody, BBS9 antibody, bbs9 antibody, Bbs9 antibody
- Background
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Synonyms: B1, D1, C18, PTHB1, Protein PTHB1, Bardet-Biedl syndrome 9 protein, Parathyroid hormone-responsive B1 gene protein, BBS9
Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.
- Gene ID
- 27241
- UniProt
- Q3SYG4
- Pathways
- Hedgehog Signaling
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