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SPEF2 antibody (AA 227-275) (AbBy Fluor® 555)

SPEF2 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 555
Catalog No. ABIN1391561
  • Target See all SPEF2 Antibodies
    SPEF2 (Sperm Flagellar 2 (SPEF2))
    Binding Specificity
    • 14
    • 4
    • 3
    • 1
    AA 227-275
    Reactivity
    Human
    Host
    • 18
    • 4
    Rabbit
    Clonality
    • 19
    • 3
    Polyclonal
    Conjugate
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPEF2 antibody is conjugated to AbBy Fluor® 555
    Application
    • 18
    • 12
    • 12
    • 10
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human KPL2/Sperm Flagellar 2
    Isotype
    IgG
    Top Product
    Discover our top product SPEF2 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SPEF2 (Sperm Flagellar 2 (SPEF2))
    Alternative Name
    KPL2/Sperm Flagellar 2 (SPEF2 Products)
    Synonyms
    si:ch211-149f21.2 antibody, CT122 antibody, KPL2 antibody, C230086A09Rik antibody, Kpl2 antibody, sperm flagellar 2 antibody, sperm flagellar 2 L homeolog antibody, sperm flagellar protein 2 antibody, SPEF2 antibody, spef2.L antibody, spef2 antibody, LOC100460730 antibody, Spef2 antibody
    Background

    Synonyms: KPL2, MGC102842, Protein KPL2, SPEF2, sperm flagellar protein 2, FLJ23164, FLJ23577, FLJ25395, KIAA1770, SPEF2_HUMAN.

    Background: Flagella and cillia are both membrane-bound projections from the cell surface that beat in distinctive patterns. Cilia are shorter and usually more profuse than flagella and contain a microtubule cytoskeleton, the ciliary axoneme, surrounded by a ciliary membrane. The ciliary membranes of all cilia hold specific receptors and ion channel proteins that initiate signaling pathways that regulate motility and/or link mechanical or chemical stimuli to intracellular transduction cascades regulating differentiation, migration and cell growth during development and in adulthood. KPL2, also known as SPEF2 (sperm flagellar 2), is a 1,822 amino acid protein that contains a calponin homology domain, three nuclear localization signals, a consensus P-loop and a proline-rich region. Required for correct axoneme develoment, KPL2 is predominantly expressed in cells with cilia or flagella. Four isoforms of KPL2 exists as a result of alternative splicing events.

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