Advillin antibody (AA 151-250) (AbBy Fluor® 555)

Catalog No. ABIN1391351

Product Details anti-Advillin Antibody (AbBy Fluor® 555)

Target: Advillin (AVIL)

Binding Specificity: AA 151-250

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Advillin antibody is conjugated to AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Advillin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Advillin

Target: Advillin (AVIL)

Alternative Name: Advillin (AVIL Products)

Synonyms: Adv antibody, SpAdv antibody, villin antibody, zgc:136857 antibody, ADVIL antibody, DOC6 antibody, p92 antibody, Advil antibody, advillin antibody, AVIL antibody, adv antibody, avil antibody, CpipJ_CPIJ004696 antibody, Avil antibody

Background:

Synonyms: Actin binding protein DOC 6, Actin binding protein DOC6, Advil, Advillin, AVIL, AVIL_HUMAN, DOC 6, DOC6, p92.

Background: Advillin is an 819 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one HP domain and six gelsolin-like repeats. Expressed at high levels in colon and small intestine and at lower levels in uterus, thymus, testis and prostate, advillin functions as a calcium-regulated Actin-binding protein that may be involved in the development of neuronal cells, specifically those that form ganglia. The gene encoding advillin maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.

Gene ID: 3316

Pathways: Regulation of Actin Filament Polymerization