NMUR2 antibody (AA 181-230) (AbBy Fluor® 488)
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- Target See all NMUR2 Antibodies
- NMUR2 (Neuromedin U Receptor 2 (NMUR2))
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Binding Specificity
- AA 181-230
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NMUR2 antibody is conjugated to AbBy Fluor® 488
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human NMUR2
- Isotype
- IgG
- Top Product
- Discover our top product NMUR2 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- NMUR2 (Neuromedin U Receptor 2 (NMUR2))
- Alternative Name
- NMUR2/GPR-FM4 (NMUR2 Products)
- Synonyms
- NMUR2 antibody, NMSR2 antibody, FM-4 antibody, FM4 antibody, NMU-R2 antibody, NMU2R antibody, TGR-1 antibody, TGR1 antibody, Nmu2r antibody, neuromedin U receptor 2 antibody, NMUR2 antibody, Nmur2 antibody
- Background
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Synonyms: FM4, G protein coupled receptor FM 4, G protein coupled receptor TGR 1, G-protein coupled receptor FM-4, G-protein coupled receptor TGR-1, Neuromedin U receptor 2, Neuromedin-U receptor 2, NMU R2, NMU-R2, NMU2R, NMUR2, NMUR2_HUMAN, TGR1
Background: Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It?s expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues.
- Gene ID
- 56923
- UniProt
- Q9GZQ4
- Pathways
- Feeding Behaviour
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