Syntaxin 12 antibody (AA 101-200) (AbBy Fluor® 488)

Catalog No. ABIN1390918

Product Details anti-Syntaxin 12 Antibody (AbBy Fluor® 488)

Target: Syntaxin 12 (STX12)

Binding Specificity: AA 101-200

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 12 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat Syntaxin 13

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Syntaxin 12

Target: Syntaxin 12 (STX12)

Alternative Name: Syntaxin 13 (STX12 Products)

Synonyms: stx12 antibody, MGC76236 antibody, zgc:86632 antibody, STX12 antibody, AI850350 antibody, AU041521 antibody, Stx13 antibody, STX13 antibody, STX14 antibody, syntaxin 12 antibody, stx12 antibody, STX12 antibody, Stx12 antibody

Background:

Synonyms: Syntaxin13, Syntaxin 13, Syntaxin-13, Syx13, Syx 13, Syx-13, CG11278, CT31479, Dm Syx13, ff16, l301470, STX12_RAT.

Background: Syntaxin 13 is an integral membrane protein that belongs to the t-SNARE family, a group of proteins involved in protein transport. Confocal immunofluoresence and electron microscopy studies have shown that syntaxin 13 is primarily localized to tubular early and recycling endosomes, where it colocalizes with transferrin receptor, and it is also localized in endosomal vacuoles. Syntaxin 13 has been found to be expressed in all tissues, with higher levels of the protein found in brain, lung, spleen, thymus and testes. Immunoprecipitation studies show that syntaxin 13 complexes with beta-SNAP, VAMP2/3, and SNAP25. The binding of this complex to alpha-SNAP and NSF is terminated in the presence of ATP. These results suggest that syntaxin 13 is a SNARE protein which mediates the recycling protein flow through tubulo vesicular recycling endosomes.

Gene ID: 65033

Pathways: Synaptic Vesicle Exocytosis