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Membralin antibody (AA 161-260) (AbBy Fluor® 488)

TMEM259 Reactivity: Zebrafish (Danio rerio) WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN1390582
  • Target See all Membralin (TMEM259) products
    Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))
    Binding Specificity
    • 14
    • 2
    • 1
    • 1
    AA 161-260
    Reactivity
    • 16
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Zebrafish (Danio rerio)
    Host
    • 21
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Membralin antibody is conjugated to AbBy Fluor® 488
    Application
    • 21
    • 12
    • 12
    • 5
    • 5
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Zebrafish (Danio rerio)
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Membralin
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))
    Alternative Name
    Membralin/C19orf6 (TMEM259 Products)
    Synonyms
    ASBABP1 antibody, C19orf6 antibody, MBRL antibody, MEMBRALIN antibody, R32184_3 antibody, C28H19orf6 antibody, c19orf6 antibody, AC087114.7gm12 antibody, AC087114.7gm2 antibody, ORF61 antibody, mFLJ00277 antibody, Mbrl antibody, RGD1311136 antibody, transmembrane protein 259 antibody, transmembrane protein 259 L homeolog antibody, TMEM259 antibody, tmem259.L antibody, Tmem259 antibody
    Background

    Synonyms: ASBABP1, C19orf6, MGC4022, R32184_3, aspecic BCL2 ARE-binding protein 1, C19orf6, chromosome 19 open reading frame 6, MBRL, MBRL_HUMAN.

    Background: The gene encoding human Membralin, C19orf6, localizes to chromosome 19p13.3. It contains 11 exons, which encode at least two splice variants in human cancer. Membralin is a multi-pass membrane protein and exists either as a long or short form. The long form of Membralin comprises all 11 exons, while the short form contains all exons except exon 10. Expression of different Membralin isoforms depends on tissue type. The long form is expressed in ovarian and colorectal carcinomas, whereas the short form is expressed in breast or pancreatic carcinomas. Because Membralin expression in ovarian carcinomas is highest in serous carcinomas as compared to surface epithelium carcinomas, expression of Membralin may be useful as a novel tumor-associated marker in ovarian serous carcinomas.

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