INSL3 antibody (AA 11-110) (AbBy Fluor® 488)

Catalog No. ABIN1390456

Product Details anti-INSL3 Antibody (AbBy Fluor® 488)

Target: INSL3 (Insulin-Like 3 (Leydig Cell) (INSL3))

Binding Specificity: AA 11-110

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSL3 antibody is conjugated to AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human INSL3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for INSL3

Target: INSL3 (Insulin-Like 3 (Leydig Cell) (INSL3))

Alternative Name: INSL3 (INSL3 Products)

Synonyms: INSL3 antibody, Rlf antibody, Rlnl antibody, RLF antibody, RLNL antibody, ley-I-L antibody, BLEYI-L antibody, LEY I-L antibody, Ley-I-L antibody, insulin like 3 antibody, insulin-like 3 antibody, Janus kinase 3 antibody, INSL3 antibody, Insl3 antibody, JAK3 antibody

Background:

Synonyms: INSL 3, INSL-3, INSL3_HUMAN, Insulin like 3, Insulin-like 3 A chain, Ley IL, Ley-I-L, Leydig insulin like peptide, Leydig insulin-like peptide, Relaxin like factor, Relaxin-like factor, RLF, RLNL.

Background: This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012].

Pathways: Hormone Activity, cAMP Metabolic Process