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LRRTM1 antibody (AA 151-250) (FITC)

LRRTM1 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal FITC
Catalog No. ABIN1389944
  • Target See all LRRTM1 Antibodies
    LRRTM1 (Leucine Rich Repeat Transmembrane Neuronal 1 (LRRTM1))
    Binding Specificity
    • 14
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    Reactivity
    • 40
    • 18
    • 10
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 38
    • 3
    Rabbit
    Clonality
    • 38
    • 3
    Polyclonal
    Conjugate
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LRRTM1 antibody is conjugated to FITC
    Application
    • 40
    • 16
    • 14
    • 12
    • 12
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Pig,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human LRRTM1
    Isotype
    IgG
    Top Product
    Discover our top product LRRTM1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    LRRTM1 (Leucine Rich Repeat Transmembrane Neuronal 1 (LRRTM1))
    Alternative Name
    LRRTM1 (LRRTM1 Products)
    Synonyms
    im:6904481 antibody, 4632401D06Rik antibody, AW125451 antibody, leucine rich repeat transmembrane neuronal 1 antibody, lrrtm1 antibody, LRRTM1 antibody, Lrrtm1 antibody
    Background

    Synonyms: Leucine rich repeat transmembrane neuronal 1, Leucine rich repeat transmembrane neuronal 1 protein, Leucine-rich repeat transmembrane neuronal protein 1, LRRT1_HUMAN, LRRTM1, Lrrtm1 leucine rich repeat transmembrane neuronal 1, OTTHUMP00000194829, 4632401D06Rik, AW125451, FLJ32082.

    Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRTM1 (leucine rich repeat transmembrane neuronal 1) is a 522 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum and contains ten LRR repeats. Expressed predominately in forebrain tissue, LRRTM1 is thought to be involved in the development of forebrain structures, specifically by influencing axon trafficking, as well as neuronal differentiation and connectivity. Human LRRTM1 shares 96 % amino acid identity with its mouse counterpart, suggesting a conserved role between species. Defects in the gene encoding LRRTM1 may be associated with the pathogenesis of several common neurodevelopmental disorders.

    Pathways
    Synaptic Membrane
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