PLAGL1 antibody (AA 1-100) (Biotin)

Catalog No. ABIN1389901

Product Details anti-PLAGL1 Antibody (Biotin)

Target: PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))

Binding Specificity: AA 1-100

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLAGL1 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Pig,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PLAGL1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PLAGL1

Target: PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))

Alternative Name: PLAGL1/ZAC1 (PLAGL1 Products)

Synonyms: PLAGL1 antibody, LOT1 antibody, ZAC antibody, ZAC1 antibody, Lot1 antibody, Zac1 antibody, PLAG1 like zinc finger 1 antibody, uncharacterized LOC100350914 antibody, pleiomorphic adenoma gene-like 1 antibody, PLAGL1 antibody, LOC100350914 antibody, Plagl1 antibody

Background:

Synonyms: DKFZp781P1017, Lost on transformation 1, Lost on Transformation, LOT-1, LOT1, MGC126275, MGC126276, PLAG like 1, PLAGL1, PLAL1_HUMAN, Pleiomorphic adenoma gene like 1, Pleiomorphic adenoma gene like protein 1, Pleiomorphic adenoma-like protein 1, Tumor supressor ZAC, ZAC, ZAC tumor supressor, ZAC1, Zinc finger protein PLAGL1.

Background: This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene. [provided by RefSeq, Oct 2010].