Chromosome 11open Reading Frame 9 (C11orf9) (AA 401-500) antibody (AbBy Fluor® 555)
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- Target See all Chromosome 11open Reading Frame 9 (C11orf9) Antibodies
- Chromosome 11open Reading Frame 9 (C11orf9)
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Binding Specificity
- AA 401-500
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- AbBy Fluor® 555
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MYRF
- Isotype
- IgG
- Top Product
- Discover our top product C11orf9 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Chromosome 11open Reading Frame 9 (C11orf9)
- Alternative Name
- MYRF/C11orf9 (C11orf9 Products)
- Synonyms
- C11orf9 antibody, c11orf9 antibody, mrf antibody, ndt80 antibody, MRF antibody, Ndt80 antibody, pqn-47 antibody, 6030439E18 antibody, Gm1804 antibody, Gm98 antibody, Mrf antibody, chromosome 5 open reading frame, human C11orf9 antibody, myelin regulatory factor L homeolog antibody, myelin regulatory factor antibody, C5H11ORF9 antibody, myrf.L antibody, MYRF antibody, Myrf antibody
- Background
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Synonyms: MRF, Ndt80, pqn-47, C11orf9, Myelin regulatory factor, Myelin gene regulatory factor, MYRF, KIAA0954
Background: Myelin regulatory factor: Consitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes (PubMed:23966832). Myelin regulatory factor, C-terminal: Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage. Myelin regulatory factor, N-terminal: Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifically recognizes and binds DNA sequence 5'-CTGGYAC-3' in the regulatory regions of myelin-specific genes and directly activates their expression. Not only required during oligodendrocyte differentiation but is also required on an ongoing basis for the maintenance of expression of myelin genes and for the maintenance of a mature, viable oligodendrocyte phenotype (PubMed:23966832).
- Gene ID
- 745
- UniProt
- Q9Y2G1
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