PCDH17 antibody (AA 31-130) (AbBy Fluor® 350)

Catalog No. ABIN1389327

Product Details anti-PCDH17 Antibody (AbBy Fluor® 350)

Target: PCDH17 (Protocadherin 17 (PCDH17))

Binding Specificity: AA 31-130

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDH17 antibody is conjugated to AbBy Fluor® 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDH17

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PCDH17

Target: PCDH17 (Protocadherin 17 (PCDH17))

Alternative Name: PCDH17 (PCDH17 Products)

Synonyms: PCDH68 antibody, PCH68 antibody, C030033F14Rik antibody, Gm78 antibody, protocadherin 17 antibody, PCDH17 antibody, Pcdh17 antibody

Background:

Synonyms: PCDH68, C030033F14Rik, Gm78, PCD17_HUMAN, PCDH17, PCDH-17, PCDH 17, PCH68, Protocadherin 17, Protocadherin 68, Protocadherin-17, Protocadherin-68.

Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH17 is a 1,159 amino acid single-pass type I membrane protein that contains six cadherin domains. Expressed as multiple alternatively spliced isoforms, PCDH17 is thought to function as a calcium-dependent cell adhesion protein that may play a role in establishing cell-cell connections within brain tissue. The gene encoding PCDH17 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4 % of the human genome.