PCDH7 antibody (AA 431-530) (Biotin)

Catalog No. ABIN1389181

Product Details anti-PCDH7 Antibody (Biotin)

Target: PCDH7 (Protocadherin 7 (PCDH7))

Binding Specificity: AA 431-530

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDH7 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDH7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PCDH7

Target: PCDH7 (Protocadherin 7 (PCDH7))

Alternative Name: PCDH7 (PCDH7 Products)

Synonyms: BH-Pcdh antibody, BHPCDH antibody, protocadherin 7 antibody, PCDH7 antibody, Pcdh7 antibody

Background:

Synonyms: BHPCDH, BH-Pcdh, PPP1R120, Protocadherin-7, Brain-heart protocadherin, PCDH7

Background: As a subfamily of the cadherin superfamily, protocadherins are cadherin-like cell adhesion proteins that contain up to seven extracellular domains and are predominantly expressed in the nervous system. Importantly, the adhesion mechanism of protocadherins is distinct from classic cadherins. Through inactivation or overexpression, several protocadherins have been implicated in a variety of cancers. PCDH7 (protocadherin 7), also known as BHPCDH or BH-Pcdh, is a 1069 amino acid single-pass I membrane protein that is expressed in the brain and heart. Containing seven cadherin domains, PCDH7 is thought to function in cell-cell recognition and adhesion. PCDH7 exists as three isoforms due to alternative splicing events.

Gene ID: 5099

UniProt: O60245