MPZL2 antibody (AA 61-160) (Biotin)

Catalog No. ABIN1389151

Product Details anti-MPZL2 Antibody (Biotin)

Target: MPZL2 (Myelin Protein Zero-Like 2 (MPZL2))

Binding Specificity: AA 61-160

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPZL2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MPZL2/EVA1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MPZL2

Target: MPZL2 (Myelin Protein Zero-Like 2 (MPZL2))

Alternative Name: MPZL2/EVA1 (MPZL2 Products)

Synonyms: cb837 antibody, eva1 antibody, mpzl2 antibody, wu:fb07b02 antibody, EVA1 antibody, EVA antibody, Eva antibody, Eva1 antibody, myelin protein zero-like 2b antibody, myelin protein zero like 2 antibody, myelin protein zero-like 2 antibody, mpzl2b antibody, MPZL2 antibody, Mpzl2 antibody

Background:

Synonyms: Epithelial V like antigen 1, epithelial V-like antigen, EVA, EVA1, MPZL2, MPZL2 myelin protein zero like 2, myelin protein zero-like 2, Myelin protein zero like protein 2, MPZL2_HUMAN.

Background: Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain, a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].