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KERA antibody (AA 201-300) (AbBy Fluor® 488)

KERA Reactivity: Human, Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN1388992
  • Target See all KERA Antibodies
    KERA (Keratocan (KERA))
    Binding Specificity
    • 14
    • 11
    • 10
    • 7
    • 2
    • 1
    • 1
    • 1
    AA 201-300
    Reactivity
    • 35
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 36
    • 1
    Rabbit
    Clonality
    • 37
    Polyclonal
    Conjugate
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KERA antibody is conjugated to AbBy Fluor® 488
    Application
    • 36
    • 17
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Keratocan
    Isotype
    IgG
    Top Product
    Discover our top product KERA Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    KERA (Keratocan (KERA))
    Alternative Name
    Keratocan (KERA Products)
    Synonyms
    KERA antibody, si:dkeyp-38g8.3 antibody, zgc:136259 antibody, CNA2 antibody, SLRR2B antibody, keratocan antibody, KERA antibody, kera antibody, Kera antibody
    Background

    Synonyms: CNA2, KERA, KERA_HUMAN, Keratan sulfate proteoglycan keratocan, Keratocan, KTN, SLRR2B.

    Background: Small leucine-rich proteoglycans (SLRPs) such as Decorin, Biglycan, Fibromod-ulin, Keratocan, Lumican and Osteoglycin mediate extracellular matrix organization and are binding partners of TGF Beta. The Decorin core protein binds to growth factors, intercellular matrix molecules such as Fibronectin and Throm-bospondin, and to the Decorin endocytosis receptor. Fibromodulin is a collagen-binding keratan sulphate proteoglycan that influences adhesion processes of connective tissue and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness. Keratocan (KTN) develops corneal transparency and maintains the stromal matrix structure. Keratocan is a secreted protein in the extracellular matrix that binds to keratan sulfate chains. Keratocan is mainly detected in the cornea, but can also be expressed in trachea, intestine, ovary, lung and skeletal muscle. Defects in the gene encoding for Keratocan can cause cornea plana 2 (CNA2), an autosomal recessive disorder where the forward convex curvature of the cornea is flattened.

    Pathways
    Glycosaminoglycan Metabolic Process
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