HAPLN2 antibody (AA 21-120) (Biotin)

Catalog No. ABIN1388977

Product Details anti-HAPLN2 Antibody (Biotin)

Target: HAPLN2 (Hyaluronan and Proteoglycan Link Protein 2 (HAPLN2))

Binding Specificity: AA 21-120

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAPLN2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HAPLN2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for HAPLN2

Target: HAPLN2 (Hyaluronan and Proteoglycan Link Protein 2 (HAPLN2))

Alternative Name: HAPLN2 (HAPLN2 Products)

Synonyms: HAPLN2 antibody, fj51g03 antibody, wu:fj51g03 antibody, si:dkey-235h8.3 antibody, BRAL1 antibody, 4930401E20Rik antibody, Bral1 antibody, hyaluronan and proteoglycan link protein 2 antibody, HAPLN2 antibody, hapln2 antibody, Hapln2 antibody

Background:

Synonyms: Brain link protein 1, Bral1, Hapln2, HPLN2_HUMAN, Hyaluronan and proteoglycan link protein 2.

Background: HAPLN2 is a 340 amino acid protein encoded by the human gene HAPLN2. HAPLN2 belongs to the HAPLN family and contains one immunoglobulin (Ig)-like, V-type domain and two link domains. HAPLN2 mediates a firm binding of versican V2 to hyaluronic acid. HAPLN2 is believed to play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS), which facilitates neuronal conduction and general structural stabilization. HAPLN2 may also be involved in the formation of extracellular matrices, contributing to perineuronal nets and facilitating the understanding of a functional role of these extracellular matrices. HAPLN2 is found in several nuclei throughout the midbrain and hindbrain in a perineuronal net pattern.