STXBP6 antibody (AA 1-100) (AbBy Fluor® 555)
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- Target See all STXBP6 Antibodies
- STXBP6 (Syntaxin Binding Protein 6 (Amisyn) (STXBP6))
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Binding Specificity
- AA 1-100
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This STXBP6 antibody is conjugated to AbBy Fluor® 555
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Cow,Sheep,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Amisyn
- Isotype
- IgG
- Top Product
- Discover our top product STXBP6 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- STXBP6 (Syntaxin Binding Protein 6 (Amisyn) (STXBP6))
- Alternative Name
- Amisyn (STXBP6 Products)
- Synonyms
- MGC68796 antibody, zgc:86678 antibody, wu:fd20e06 antibody, amisyn antibody, hspc156 antibody, MGC88977 antibody, STXBP6 antibody, LOC100226852 antibody, BC024598 antibody, C85317 antibody, Amisyn antibody, syntaxin binding protein 6 L homeolog antibody, syntaxin binding protein 6 (amisyn) antibody, syntaxin binding protein 6 antibody, stxbp6.L antibody, stxbp6 antibody, STXBP6 antibody, Stxbp6 antibody
- Background
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Synonyms: Amisyn, HSPC156, STXB6_HUMAN, STXBP6, Syntaxin binding protein 6, Syntaxin-binding protein 6.
Background: Amisyn is a mostly cytosolic protein related to Tomosyn which plays an important role in SNARE complex assembly. Amisyn contains a v-SNARE coiled coil homology domain that binds to Syntaxin 1A and weakly to Syntaxin 4. Three isoforms exist for Amisyn. Isoform 1 is the full length protein, isoform 2 has a different amino acid sequence between residues 204-210 and isoform 3 is missing amino acids 1-102 and contains a different sequence for amino acids 103-150. Amisyn lacks a transmembrane domain and therefore is unable to assemble into a functional, membrane-anchored SNARE complex. This suggests that Amisyn may instead be acting to maintain SNARE conformation and facilitate the binding of VAMP-2. Amisyn can inhibit exocytosis independent of Syntaxin binding.
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