GLIPR2 antibody (AA 51-154)

Catalog No. ABIN1388014

Product Details anti-GLIPR2 Antibody

Target: GLIPR2 (GLI Pathogenesis-Related 2 (GLIPR2))

Binding Specificity: AA 51-154

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLIPR2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GLIPR2

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GLIPR2

Target: GLIPR2 (GLI Pathogenesis-Related 2 (GLIPR2))

Alternative Name: GLIPR2 (GLIPR2 Products)

Synonyms: fd05a10 antibody, im:6795575 antibody, wu:fd05a10 antibody, si:dkey-2n12.1 antibody, C9orf19 antibody, GAPR-1 antibody, GAPR1 antibody, 5730414A08Rik antibody, C77180 antibody, C8H9ORF19 antibody, GLI pathogenesis-related 2 antibody, GLI pathogenesis related 2 antibody, glipr2 antibody, GLIPR2 antibody, Glipr2 antibody

Background:

Synonyms: GAPR 1, GAPR-1, GAPR1_HUMAN, GLI pathogenesis related 2, Glioma pathogenesis related protein 2, Glioma pathogenesis-related protein 2, GliPR 2, GLIPR2, Golgi associated plant pathogenesis related protein 1, Golgi associated PR 1 protein, Golgi-associated plant pathogenesis-related protein 1, Golgi-associated PR-1 protein, OTTMUSP00000007558, RP11-421H8.5, RP23-209M8.2, C77180, 5730414A08Rik, C9orf19.

Background: Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. GAPR-1 (Golgi-associated plant pathogenesis-related protein 1), also known as GLIPR2, is a 154 amino acid lipid anchor protein belonging to the CRISP family. GAPR-1 also shares similarity with the pathogenesis-related protein (PR) superfamily, and may play an important role in the immune system. Existing as a homodimer, GAPR-1 is highly expressed in lung and peripheral leukocytes with minor expression in liver and kidney. Containing a conserved sperm-coating protein (SCP) domain, GAPR-1 binds to negatively charged lipids and may be involved in the differentiation of epithelial cells into mesenchymal cells. Increased expression of GAPR-1 in kidney may contribute to the development of fibrosis.