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GHDC antibody (AA 201-300)

GHDC Reactivity: Human WB, ELISA, IHC (p), IF (p), IHC (fro), IF (cc) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1388012
  • Target See all GHDC Antibodies
    GHDC (GH3 Domain Containing (GHDC))
    Binding Specificity
    • 3
    • 2
    • 1
    • 1
    AA 201-300
    Reactivity
    • 15
    • 3
    • 2
    Human
    Host
    • 13
    • 2
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GHDC antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GHDC
    Isotype
    IgG
    Top Product
    Discover our top product GHDC Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    GHDC (GH3 Domain Containing (GHDC))
    Alternative Name
    GHDC (GHDC Products)
    Synonyms
    D11LGP1 antibody, LGP1 antibody, D11Lgp1e antibody, RGD1308881 antibody, GH3 domain containing antibody, GHDC antibody, Ghdc antibody
    Background

    Synonyms: D11LGP1, D11LGP1E, D11lgp1e like, GH3 domain containing, GH3 domain containing protein, GH3 domain-containing protein, GHDC, GHDC_HUMAN, Homolog of mouse LGP1, LGP1.

    Background: Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dub? syndrome and Canavan disease are also associated with chromosome 17.

    Gene ID
    84514
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