HEATR3 antibody (AA 601-680)

Catalog No. ABIN1388001

Product Details anti-HEATR3 Antibody

Target: HEATR3 (HEAT Repeat Containing 3 (HEATR3))

Binding Specificity: AA 601-680

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEATR3 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HEATR3

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HEATR3

Target: HEATR3 (HEAT Repeat Containing 3 (HEATR3))

Alternative Name: HEATR3 (HEATR3 Products)

Synonyms: RGD1308267 antibody, SYO1 antibody, C030036P15Rik antibody, HEAT repeat containing 3 antibody, Heatr3 antibody, HEATR3 antibody

Background:

Synonyms: HEAT repeat-containing protein 3, HEAT repeat containing 3, HEAT3_HUMAN, Heatr3.

Background: HEATR3 is a 680 amino acid protein existing as three alternatively spliced isoforms and containing two HEAT (Huntingtin, elongation factor 3 (EF3), protein phosphatase 2A (PP2A) and the yeast PI3-kinase Tor1) repeats. HEAT repeats form rod-like helical structures that are involved in intracellular transport. HEATR3 is encoded by a gene located on human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition.

Gene ID: 55027

Pathways: SARS-CoV-2 Protein Interactome