COX4NB antibody (AA 121-210)

Catalog No. ABIN1387995

Product Details anti-COX4NB Antibody

Target: COX4NB (COX4 Neighbor (COX4NB))

Binding Specificity: AA 121-210

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX4NB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COX4NB

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for COX4NB

Target: COX4NB (COX4 Neighbor (COX4NB))

Alternative Name: Cox4nb (COX4NB Products)

Synonyms: COX4NB antibody, NOC4 antibody, MGC75783 antibody, cox4nb antibody, fb54g02 antibody, noc4 antibody, wu:fb54g02 antibody, zgc:56331 antibody, C16orf2 antibody, C16orf4 antibody, FAM158B antibody, Cox4nb antibody, Fam158b antibody, Noc4 antibody, ER membrane protein complex subunit 8 antibody, ER membrane protein complex subunit 8 S homeolog antibody, ER membrane protein complex subunit 9 antibody, EMC8 antibody, emc8 antibody, emc8.S antibody, EMC9 antibody, Emc8 antibody

Background:

Synonyms: C16orf4, COX4 neighbor, Neighbor of COX4, COX4AL, Cox4nb, CX4NB_HUMAN, Neighbor of COX4, NOC4, EMC8, C16orf2, Protein FAM158B.

Background: COX4NB is a 210 amino acid protein encoded by the human gene COX4NB. COX4NB belongs to the UPF0172 (NOC4) family and is found on chromosome 16, adjacent to the gene that encodes COX4. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16 through the CREBBP gene which encodes a critical CREB binding protein. Crohn?s disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other auto-immune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.

Gene ID: 10328