DHRS7 antibody (AA 61-160)

Catalog No. ABIN1387988

Product Details anti-DHRS7 Antibody

Target: DHRS7 (Dehydrogenase/reductase (SDR Family) Member 7 (DHRS7))

Binding Specificity: AA 61-160

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHRS7 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DHRS7

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DHRS7

Target: DHRS7 (Dehydrogenase/reductase (SDR Family) Member 7 (DHRS7))

Alternative Name: Dhrs7 (DHRS7 Products)

Synonyms: DR-NR3 antibody, MGC80755 antibody, MGC107821 antibody, MGC197379 antibody, MGC197409 antibody, zgc:154087 antibody, SDR34C1 antibody, retDSR4 antibody, retSDR4 antibody, 2310016E22Rik antibody, 5730564L20Rik antibody, AW061210 antibody, Retdsr4 antibody, Retsdr4 antibody, dehydrogenase/reductase (SDR family) member 7-like 1 antibody, dehydrogenase/reductase 7 antibody, dehydrogenase/reductase (SDR family) member 7 L homeolog antibody, dehydrogenase/reductase (SDR family) member 7 antibody, Dhrs7l1 antibody, DHRS7 antibody, dhrs7.L antibody, dhrs7 antibody, Dhrs7 antibody

Background:

Synonyms: CGI 86, CGI86, Dehydrogenase/reductase SDR family member 7, DHRS7A, retDSR4, Retinal short chain dehydrogenase/reductase 4, RETSDR4, DHRS7_HUMAN.

Background: DHRS7 (dehydrogenase/reductase (SDR family) member 7), also known as SDR34C1, CGI-86 or retSDR4, is a 339 amino acid member of the SDR family. Like other members of the SDR family, DHRS7 contains a cofactor-binding Rossman-fold domain and is thought to catalyze the oxidation and reduction of a variety of substrates such as steroids and retinoids. DHRS7 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 14, which houses over 700 genes and comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Gene ID: 51635