Prolactin Receptor antibody (AA 251-350)

Catalog No. ABIN1387937

Product Details anti-Prolactin Receptor Antibody

Target: Prolactin Receptor (PRLR)

Binding Specificity: AA 251-350

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prolactin Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Prolactin Receptor

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Alternative Name: PRLR (PRLR Products)

Synonyms: hPRLrI antibody, PRL-R antibody, prlr antibody, PRLRb antibody, PRLR antibody, tprlr antibody, DKFZp469D061 antibody, RATPRLR antibody, AI987712 antibody, Pr-1 antibody, Pr-3 antibody, Prlr-rs1 antibody, wu:fj65c07 antibody, prolactin receptor antibody, prolactin receptor L homeolog antibody, prolactin receptor S homeolog antibody, prolactin receptor a antibody, PRLR antibody, prlr.L antibody, prlr.S antibody, PR antibody, prlr antibody, Prlr antibody, prlra antibody

Background:

Synonyms: HPRL, MFAB, hPRLrI, Prolactin receptor, PRL-R, PRLR

Background: This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.

Gene ID: 5618

UniProt: P16471

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus