CRTAM antibody (AA 31-130)

Catalog No. ABIN1387894

Product Details anti-CRTAM Antibody

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Binding Specificity: AA 31-130

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTAM antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRTAM

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CRTAM antibody (ABIN1387894)

Hinman, Ngo, Kim, Chen, Abraham, Ghanbari, Ikram, Kushner, Kawaguchi, Coppola, Goth, Bellusci, Hernandez, Kosik, Fogel: "miR-142-3p Regulates Cortical Oligodendrocyte Gene Co-expression Networks Associated with Tauopathy." in: Human molecular genetics, (2021) (PubMed).

Target Details for CRTAM

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Alternative Name: CRTAM (CRTAM Products)

Synonyms: TAD antibody, cTADS antibody, MGC82176 antibody, CRTAM antibody, CD355 antibody, cytotoxic and regulatory T-cell molecule antibody, cytotoxic and regulatory T-cell molecule L homeolog antibody, cytotoxic and regulatory T cell molecule antibody, CRTAM antibody, crtam.L antibody, Crtam antibody

Background:

Synonyms: CD355, Cytotoxic and regulatory T-cell molecule, Class-I MHC-restricted T-cell-associated molecule, CRTAM

Background: Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

Gene ID: 56253

UniProt: O95727

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation