LHX4 antibody (AA 171-280)
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- Target See all LHX4 Antibodies
- LHX4 (LIM Homeobox 4 (LHX4))
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Binding Specificity
- AA 171-280
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LHX4 antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Lhx4
- Isotype
- IgG
- Top Product
- Discover our top product LHX4 Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- LHX4 (LIM Homeobox 4 (LHX4))
- Alternative Name
- Lhx4 (LHX4 Products)
- Synonyms
- LHX4 antibody, si:dkeyp-35f11.3 antibody, CPHD4 antibody, A330062J17Rik antibody, Gsh-4 antibody, Gsh4 antibody, LIM homeobox 4 antibody, LIM homeobox protein 4 antibody, LHX4 antibody, lhx4 antibody, Lhx4 antibody
- Background
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Synonyms: Gsh 4, Gsh4, Lhx4, LHX4_HUMAN, LIM Homeobox 4, LIM homeobox protein 4, LIM/homeobox protein Lhx4.
Background: The LIM domain (a zinc finger structure) is a protein-protein interaction motif found in several protein types, including homeodomain transcription factors and kinases, which has a role in many cellular processes. The LIM family of homeodomain proteins plays a role in organismal differentiation and development. Specifically, LHX4 and closely related LHX3 play essential roles in multiple developmental stages of the pituitary gland in mice. The LHX4 gene is expressed in murine fetal brain, spinal cord and cerebral cortex. In addition, LHX4 is expressed in the cerebral cortex and in the motor neurons of the CNS in adult rodents. A specific murine LHX4 gene mutation results in a short stature phenotype, pituitary and cerebelllar defects and sella turcica malformations. The LHX4 gene may be implicated in the t(1,4)(q25,q32) chromosomal translocation, which is associated with acute lymphoblastic leukemia. The LHX4 gene is also expressed in leukemic cells and may activate leukemogenesis. The human LHX4 gene maps to chromosome 1q25 and encodes a 390 amino acid protein.
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