LCA5 antibody

Catalog No. ABIN1387805

Product Details anti-LCA5 Antibody

Target: LCA5 (Leber Congenital Amaurosis 5 (LCA5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LCA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LCA5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for LCA5

Target: LCA5 (Leber Congenital Amaurosis 5 (LCA5))

Alternative Name: LCA5 (LCA5 Products)

Synonyms: C6orf152 antibody, RGD1308555 antibody, 4930431B11Rik antibody, 5730406O13Rik antibody, AV274874 antibody, ORF64 antibody, LCA5, lebercilin antibody, Leber congenital amaurosis 5 antibody, Leber congenital amaurosis 5 (human) antibody, LCA5 antibody, LOC787523 antibody, Lca5 antibody

Background:

Synonyms: C6orf152, LCA5, Leber congenital amaurosis 5, Leber congenital amaurosis 5 protein, ORF64, RGD1308555.

Background: Leber congenital amaurosis (LCA) is one of the most common causes of hereditary blindness or severe visual impairment in infants. Mutations in several genes with diverse functions mapping to two loci have been implicated in LCA causation. These proteins are involved in processes such as photoreceptor development and maintenance, phototransduction, vitamin A metabolism and protein trafficking. LCA5, also known as Lebercilin, is a ciliary protein that is widely expressed during development and localizes to the connecting cilia of photoreceptors and to the microtubules, centrioles and primary cilia of cultured mammalian cells. The Leber congenital amaurosis 5-like protein (LCA5L) is a 670 amino acid protein that belongs to the LCA5 family.

Gene ID: 167691