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RAPGEF2 antibody (AA 501-600)

RAPGEF2 Reactivity: Human WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387779
  • Target See all RAPGEF2 Antibodies
    RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))
    Binding Specificity
    • 14
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 501-600
    Reactivity
    • 29
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 27
    • 2
    Rabbit
    Clonality
    • 28
    • 1
    Polyclonal
    Conjugate
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAPGEF2 antibody is un-conjugated
    Application
    • 23
    • 12
    • 12
    • 9
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RAPGEF2
    Isotype
    IgG
    Top Product
    Discover our top product RAPGEF2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))
    Alternative Name
    RAPGEF2/PDZ-GEF1 (RAPGEF2 Products)
    Synonyms
    MGC83978 antibody, RAPGEF2 antibody, fa11h07 antibody, wu:fa11h07 antibody, CNrasGEF antibody, NRAPGEP antibody, PDZ-GEF1 antibody, PDZGEF1 antibody, RA-GEF antibody, Rap-GEP antibody, nRap GEP antibody, 5830453M24Rik antibody, CNRasGEF antibody, Pdzgef1 antibody, RA-GEF-1 antibody, mKIAA0313 antibody, nRapGEP antibody, Rap guanine nucleotide exchange factor 2 antibody, Rap guanine nucleotide exchange factor 2 L homeolog antibody, Rap guanine nucleotide exchange factor (GEF) 2 antibody, RAPGEF2 antibody, rapgef2.L antibody, rapgef2 antibody, Rapgef2 antibody
    Background

    Synonyms: KIAA0313, Neural RAP guanine nucleotide exchange protein, nRap GEP, NRAPGEP, PDZ domain containing guanine nucleotide exchange factor 1, PDZ domain-containing guanine nucleotide exchange factor 1, PDZ GEF1, PDZ-GEF1, PDZGEF1, RA GEF, RA-GEF, Rap guanine nucleotide exchange factor 2, Rapgef2, RPGF2_HUMAN.

    Background: PDZ-GEF1 is a 1,499 amino acid cell membrane protein that functions as a guanine nucleotide exchange factor for Rap 1A, Rap 1B and Rap 2B GTPases. Expressed at highest levels in brain, PDZ-GEF1 is found at low levels in placenta, heart, lung and kidney, and undergoes post-translational phosphorylation following DNA damage. PDZ-GEF1 interacts with MAGI-2 and contains one Ras-GEF domain, a Ras-associating domain, one PDZ (DHR) domain, a single N-terminal Ras-GEF domain and a cyclic nucleotide-binding domain. The gene encoding PDZ-GEF1 maps to human chromosome 4q32.1.

    Pathways
    Neurotrophin Signaling Pathway
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