MAPK12 antibody (pThr183, pTyr185)
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- Target See all MAPK12 Antibodies
- MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))
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Binding Specificity
- pThr183, pTyr185
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAPK12 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human SAPK3 around the phosphorylation site of Thr183+Tyr185 [EM(p-T)G(p-Y)VV]
- Isotype
- IgG
- Top Product
- Discover our top product MAPK12 Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))
- Alternative Name
- SAPK3+ (MAPK12 Products)
- Synonyms
- ATMPK12 antibody, MAPK12 antibody, T3F17.28 antibody, mitogen-activated protein kinase 12 antibody, MGC160082 antibody, si:dkey-14d8.5 antibody, erk6 antibody, etID309866.18 antibody, mapk12 antibody, sapk3 antibody, wu:fa05c12 antibody, zgc:101695 antibody, ERK3 antibody, ERK6 antibody, P38GAMMA antibody, PRKM12 antibody, SAPK-3 antibody, SAPK3 antibody, AW123708 antibody, Erk6 antibody, P38gamma antibody, Prkm12 antibody, Sapk3 antibody, mitogen-activated protein kinase 12 antibody, mitogen-activated protein kinase 12b antibody, mitogen-activated protein kinase 12a antibody, MPK12 antibody, MAPK12 antibody, mapk12b antibody, mapk12a antibody, Mapk12 antibody
- Background
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Synonyms: p-SAPK3Thr183+Tyr185, MAP kinase 12, MAP kinase p38 gamma, MAPK 12, Mapk12, Mitogen Activated Protein Kinase 12, ERK6, ERK 6, ERK-6, Extracellular signal-regulated kinase 6, Mitogen activated protein kinase 3, Mitogen activated protein kinase p38 gamma, Mitogen-activated protein kinase 12, Mitogen-activated protein kinase p38 gamma, MK12_HUMAN, P38 GAMMA, P38GAMMA, PRKM12, SAPK 3, SAPK3, Stress Activated Protein Kinase 3, Stress-activated protein kinase 3.
Background: MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38 alpha, p38 beta and p38 gamma, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38 alpha, p38 beta and p38 gamma are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation. The p38 proteins are subject to phosphoryation on Thr and Tyr residues, an event which is thought to activate the phosphorylated protein.
- Pathways
- MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C, BCR Signaling, S100 Proteins
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