C22orf28 antibody

Catalog No. ABIN1387743

Product Details anti-C22orf28 Antibody

Target: C22orf28 (Chromosome 22 Open Reading Frame 28 (C22orf28))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C22orf28 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSPC117/C22orf28

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C22orf28

Target: C22orf28 (Chromosome 22 Open Reading Frame 28 (C22orf28))

Alternative Name: C22orf28 (C22orf28 Products)

Synonyms: C1H22orf28 antibody, C22orf28 antibody, DJ149A16.6 antibody, FAAP antibody, RP1-149A16.6 antibody, c22orf28 antibody, C10H22orf28 antibody, MGC154502 antibody, HSPC117 antibody, AI255213 antibody, AI463255 antibody, RNA 2',3'-cyclic phosphate and 5'-OH ligase antibody, tRNA-splicing ligase RtcB homolog antibody, RTCB antibody, rtcb antibody, rtcb.L antibody, Rtcb antibody

Background:

Synonyms: FAAP, Ankyrin repeat domain 54, C22orf28, Chromosome 22 open reading frame 28, DJ149A16.6, HSPC117, Hypothetical protein LOC51493, Novel protein HSPC117, RP1-149A16.6, RTCB_HUMAN, tRNA-splicing ligase RtcB homolog.

Background: HSPC117, also known as C22orf28, is a 505 amino acid protein that is encoded by a gene which maps to human chromosome 22. A highly homologous protein identified in rodents, FAAP (focal adhesion associated protein), encoded by murine D10Wsu52e gene, has been suggested to play a role in regulating cell adhesion dynamics. Chromosome 22 houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Gene ID: 51493