BAZ1A antibody (AA 1401-1556)

Catalog No. ABIN1387730

Product Details anti-BAZ1A Antibody

Target: BAZ1A (Bromodomain Adjacent To Zinc Finger Domain, 1A (BAZ1A))

Binding Specificity: AA 1401-1556

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAZ1A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATP utilizing chromatin assembly and remodeling factor 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BAZ1A

Target: BAZ1A (Bromodomain Adjacent To Zinc Finger Domain, 1A (BAZ1A))

Alternative Name: ACF1 (BAZ1A Products)

Synonyms: ACF1 antibody, WALp1 antibody, WCRF180 antibody, hACF1 antibody, fi34e04 antibody, wu:fi34e04 antibody, acf1 antibody, walp1 antibody, wcrf180 antibody, BAZ1A antibody, Acf1 antibody, B930060C03 antibody, BC065123 antibody, Gtl5 antibody, Wcrf180 antibody, cbp146 antibody, bromodomain adjacent to zinc finger domain 1A antibody, bromodomain adjacent to zinc finger domain, 1A antibody, bromodomain adjacent to zinc finger domain 1A S homeolog antibody, BAZ1A antibody, Baz1a antibody, baz1a antibody, baz1a.S antibody

Background:

Synonyms: BAZ1A, Acf1, ACF1, drosophila, homolog of antibody ATP dependent chromatin remodelling protein, ATP utilizing chromatin assembly and remodeling factor 1, ATP-dependent chromatin-remodeling protein, ATP-utilizing chromatin assembly and remodeling factor 1, Baz1a, BAZ1A_HUMAN, Bromodomain adjacent to zinc finger domain 1A, Bromodomain adjacent to zinc finger domain protein 1A, cbp146, CHRAC subunit ACF1, Gtl5.

Background: Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.Component of the histone-fold protein complex CHRAC complex which faciliates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions.

Gene ID: 11177

UniProt: Q9NRL2