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COQ10B antibody (AA 38-110)

COQ10B Reactivity: Human, Mouse WB, IF (cc), IF (p), ELISA, ICC, IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387713
  • Target See all COQ10B Antibodies
    COQ10B (Coenzyme Q10 Homolog B (COQ10B))
    Binding Specificity
    • 14
    • 1
    • 1
    AA 38-110
    Reactivity
    • 18
    • 16
    • 2
    Human, Mouse
    Host
    • 18
    • 1
    Rabbit
    Clonality
    • 18
    • 1
    Polyclonal
    Conjugate
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COQ10B antibody is un-conjugated
    Application
    • 18
    • 12
    • 12
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    Cross-reactivity with COQ10A (91 % homology with the immunogen sequence),
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human COQ10B
    Isotype
    IgG
    Top Product
    Discover our top product COQ10B Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    COQ10B (Coenzyme Q10 Homolog B (COQ10B))
    Alternative Name
    COQ10B (COQ10B Products)
    Synonyms
    1500041J02Rik antibody, 1700030I21Rik antibody, 9530077A17Rik antibody, AV002237 antibody, AW742641 antibody, RGD1359509 antibody, fc38f07 antibody, im:6912267 antibody, wu:fc38f07 antibody, zgc:112103 antibody, coenzyme Q10B antibody, COQ10B antibody, Coq10b antibody, coq10b antibody
    Background

    Synonyms: Coenzyme Q10, Coenzyme Q10 B, Coenzyme Q10 homolog B, Coenzyme Q10B, CQ10B_HUMAN.

    Background: COQ10B, Coenzyme Q10, is a 247 amino acid protein encoded by the human gene COQ10B. COQ10B is a mitochondrial protein that belongs to the COQ10 family. COQ10B is an essential biological cofactor which increases brain mitochondrial concentration and exerts neuroprotective effects. Plasma COQ10B levels decrease in patients with advanced chronic heart failure (CHF) while COQ10B levels in hyperthyroid patients are found among the lowest detected in human diseases. Likewise, COQ10B is elevated in hypothyroid subjects, also in subclinical conditions, suggesting the usefulness of this index in assessing metabolic status in thyroid disorders. It is believed that secretion of adrenal hormones is in some way related to COQ10B levels, both in augmented and reduced conditions. However, since thyroid hormones have an important role in modulating COQ10B levels and metabolism, when coexistent, thyroid deficiency seems to play a prevalent role in comparison with adrenal deficiency.

    Gene ID
    80219
    UniProt
    Q9H8M1
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