PHF21A antibody (AA 351-450)

Catalog No. ABIN1387678

Product Details anti-PHF21A Antibody

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Binding Specificity: AA 351-450

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF21A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PHF21A

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PHF21A

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Alternative Name: BHC80/PHF21A (PHF21A Products)

Synonyms: PHF21A antibody, im:7138823 antibody, si:dkey-23n7.9 antibody, BHC80 antibody, RGD1560612 antibody, 80kDa antibody, Bhc antibody, Bhc80 antibody, D030065N23Rik antibody, PFTF1 antibody, fj98d03 antibody, phf21a antibody, wu:fj98d03 antibody, PHD finger protein 21A antibody, PHD finger protein 21Aa antibody, PHD finger protein 21Ab antibody, PHF21A antibody, phf21aa antibody, pf21a antibody, phf21a antibody, LOC100549929 antibody, Phf21a antibody, phf21ab antibody

Background:

Synonyms: BHC80a, BM-006, BRAF35-HDAC complex protein BHC80, BRAF35-HDAC complex protein BHC80, BRAF35-HDAC complex protein BHC80, BRAF35/HDAC2 complex 80 kDa, KIAA1696, PF21A_HUMAN, PHD finger protein 21A, PHF21A.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.

Gene ID: 51317

Pathways: Feeding Behaviour