TMEM106B antibody (AA 101-200)

Catalog No. ABIN1387646

Product Details anti-TMEM106B Antibody

Target: TMEM106B (Transmembrane Protein 106B (TMEM106B))

Binding Specificity: AA 101-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM106B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TMEM106B

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TMEM106B antibody (ABIN1387646)

Satoh, Kino, Kawana, Yamamoto, Ishida, Saito, Arima: "TMEM106B expression is reduced in Alzheimer's disease brains." in: Alzheimer's research & therapy, Vol. 6, Issue 2, pp. 17, (2014) (PubMed).

Target Details for TMEM106B

Target: TMEM106B (Transmembrane Protein 106B (TMEM106B))

Alternative Name: TMEM106B (TMEM106B Products)

Synonyms: 2310036D22Rik antibody, 5830455K21Rik antibody, 6430519M21Rik antibody, AI428776 antibody, AI661344 antibody, LRRGT00101 antibody, MGC81788 antibody, tmem106b antibody, zgc:114147 antibody, zgc:64013 antibody, transmembrane protein 106B antibody, transmembrane protein 106B S homeolog antibody, transmembrane protein 106Bb antibody, transmembrane protein 106b antibody, transmembrane protein 106Ba antibody, TMEM106B antibody, Tmem106b antibody, tmem106b.S antibody, tmem106b antibody, tmem106bb antibody, Tsp_02056 antibody, Tsp_01553 antibody, t106b antibody, tmem106ba antibody

Background:

Synonyms: Transmembrane protein 16B, TMEM16B

Background: Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching.

Gene ID: 54664

UniProt: Q9NUM4