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AASS antibody (AA 878-926)

AASS Reactivity: Mouse WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387634
  • Target See all AASS Antibodies
    AASS (Aminoadipate Semialdehyde Synthase (AASS))
    Binding Specificity
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 878-926
    Reactivity
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Mouse
    Host
    • 19
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 16
    • 1
    • 1
    • 1
    This AASS antibody is un-conjugated
    Application
    • 15
    • 9
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human LKRSDH
    Isotype
    IgG
    Top Product
    Discover our top product AASS Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    AASS (Aminoadipate Semialdehyde Synthase (AASS))
    Alternative Name
    AASS/LKRSDH (AASS Products)
    Synonyms
    LKR/SDH antibody, LKRSDH antibody, LORSDH antibody, LKR antibody, LOR antibody, LOR/SDH antibody, Lorsdh antibody, SDH antibody, aminoadipate-semialdehyde synthase antibody, AASS antibody, Aass antibody
    Background

    Synonyms: Alpha aminoadipic semialdehyde synthase mitochondrial, LKR/SDH, LKRSDH, LORSDH, Lysine ketoglutarate reductase, Saccharopine dehydrogenase, AASS_HUMAN.

    Background: Alpha-aminoadipic semialdehyde synthase (AASS), also designated lysine ketoglutarate reductase (LKR) or saccharopine dehydrogenase (SDH), is a 926 amino acid protein that exists as a homodimer in the mitochondria. AASS acts as a bifunctional enzyme containing the lysine alpha-ketoglutarate reductase (LKR) and saccharopine dehydrogenase activities that catalyzes the first two steps in lysine degradation. It is widely expressed with highest expression in liver and transcription of the AASS gene is induced upon starvation. Mutations in the gene encoding AASS result in various forms familial hyperlysinemias (FH), autosomal recessive disorders characterized by hyperlysinemia, lysinuria, and variable saccharopinuria. However, no adverse mental or physical effects have been found in patients with hyperlysinemia.

    Gene ID
    10157
    Pathways
    SARS-CoV-2 Protein Interactome
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