Protocadherin 1 antibody (AA 51-150)

Catalog No. ABIN1387513

Product Details anti-Protocadherin 1 Antibody

Target: Protocadherin 1 (PCDH1)

Binding Specificity: AA 51-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Protocadherin 1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDH1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Protocadherin 1

Target: Protocadherin 1 (PCDH1)

Alternative Name: PCDH1 (PCDH1 Products)

Synonyms: PC42 antibody, PCDH42 antibody, 2010005A06Rik antibody, AI585920 antibody, PCDH-1 antibody, axpc antibody, protocadherin-1 antibody, pcdh1 antibody, protocadherin 1 antibody, protocadherin 1 S homeolog antibody, protocadherin 1b antibody, PCDH1 antibody, Pcdh1 antibody, pcdh1.S antibody, pcdh1b antibody

Background:

Synonyms: Cadherin like 1, Cadherin like protein 1, PC 42, PC42, PCDH 1, PCDH-1, PCDH 42, PCDH42, Protocadherin 1, Protocadherin 42, Protocadherin1, Protocadherin42.

Background: Protocadherins are a subfamily of cadherins, a large group of related glycoproteins that mediate calcium-dependent cell-to-cell adhesion via a homophilic mechanism. Involved in a variety of functions, protocadherins help to regulate neural development and synapse formation. PCDH1 is a 1,026 amino acid single-pass type I membrane protein that contains seven cadherin domains and is a member of the protocadherin family. Localized to cell-cell and cell-matrix boundaries and expressed at high levels in brain and neuro-glial cells, PCDH1 is thought to be involved in cell adhesion and cell-cell interactions and may play a role in neuronal development. PCDH1 contains a C-terminal cytoplasmic region, an extracellular region and a transmembrane region, and is expressed as two isoforms due to alternative splicing events.

Gene ID: 64121