VAX2 antibody (AA 131-205)

Catalog No. ABIN1387399

Product Details anti-VAX2 Antibody

Target: VAX2 (Ventral Anterior Homeobox 2 (VAX2))

Binding Specificity: AA 131-205

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VAX2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for VAX2

Target: VAX2 (Ventral Anterior Homeobox 2 (VAX2))

Alternative Name: VAX2 (VAX2 Products)

Synonyms: VAX2 antibody, dres93 antibody, vax3 antibody, xvax2 antibody, DRES93 antibody, Dres93 antibody, ventral anterior homeobox 2 antibody, ventral anterior homeobox 2 S homeolog antibody, VAX2 antibody, vax2.S antibody, Tsp_02192 antibody, Vax2 antibody, vax2 antibody

Background:

Synonyms: DRES93, Ventral anterior homeobox 2, VAX2_HUMAN.

Background: VAX2 is a 290 amino acid homeobox protein that plays a crucial role in development of the eye, particularly in the specification of the ventral optic vesicle and in establishment of a correct dorsoventral pattern. VAX2 acts as a transcription factor with VAX1 to cooperatively regulate retinal differentiation, neuroepithelial cell proliferation and axial polarization in the retina. Together, VAX1 and VAX2 repress transcription of Pax-6, a strong inducer of retinal development. VAX1 and VAX2 localize to the nucleus and contain one homeobox DNA-binding domain each.