MKL1 antibody (AA 201-300)

Catalog No. ABIN1387286

Product Details anti-MKL1 Antibody

Target: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Binding Specificity: AA 201-300

Reactivity: Human, Mouse, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Pig, Rat

Predicted Reactivity: Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Mkl1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MKL1

Target: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Alternative Name: Mkl1 (MKL1 Products)

Synonyms: MKL1 antibody, BSAC antibody, MAL antibody, MRTF-A antibody, Mrtf-a antibody, mrtf-a antibody, mrtfa antibody, AI852829 antibody, AMKL antibody, AW743281 antibody, AW821984 antibody, Bsac antibody, Mal antibody, Mrtf-A antibody, megakaryoblastic leukemia (translocation) 1 antibody, megakaryoblastic leukemia 1 protein antibody, megakaryoblastic leukemia (translocation) 1 S homeolog antibody, MKL (megakaryoblastic leukemia)/myocardin-like 1 antibody, MKL1 antibody, mkl1 antibody, Mkl1 antibody, mkl1.S antibody

Background:

Synonyms: MAL, BSAC, MRTF-A, MKL/myocardin-like protein 1, Megakaryoblastic leukemia 1 protein, Megakaryocytic acute leukemia protein, Myocardin-related transcription factor A, MKL1, KIAA1438

Background: Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases, its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation (By similarity).

Gene ID: 57591

UniProt: Q969V6