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HOPX antibody (AA 25-73)

HOPX Reactivity: Human, Mouse, Rat WB, IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387281
  • Target See all HOPX Antibodies
    HOPX (HOP Homeobox (HOPX))
    Binding Specificity
    • 14
    • 12
    • 9
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 25-73
    Reactivity
    • 54
    • 22
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 51
    • 4
    Rabbit
    Clonality
    • 52
    • 3
    Polyclonal
    Conjugate
    • 21
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HOPX antibody is un-conjugated
    Application
    • 44
    • 24
    • 15
    • 12
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HOPX/LAGY
    Isotype
    IgG
    Top Product
    Discover our top product HOPX Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    HOPX (HOP Homeobox (HOPX))
    Alternative Name
    LAGY (HOPX Products)
    Synonyms
    CAMEO antibody, HOD antibody, HOP antibody, LAGY antibody, NECC1 antibody, OB1 antibody, SMAP31 antibody, TOTO antibody, 1110018K11Rik antibody, 1200015P04Rik antibody, 2300002F06Rik antibody, AI848177 antibody, AW490897 antibody, Cameo antibody, Hdop antibody, Hod antibody, Hop antibody, Ob1 antibody, Obl antibody, Toto antibody, GIIg15b antibody, HOPX antibody, hod antibody, hop antibody, ob1 antibody, lagy antibody, toto antibody, cameo antibody, necc1 antibody, smap31 antibody, MGC147344 antibody, HOP homeobox antibody, HOPX antibody, Hopx antibody, hopx antibody
    Background

    Synonyms: HOD, HOP, OB1, LAGY, TOTO, CAMEO, NECC1, SMAP31, Homeodomain-only protein, Lung cancer-associated Y protein, Not expressed in choriocarcinoma protein 1, Odd homeobox protein 1, HOPX

    Background: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.

    Gene ID
    84525
    UniProt
    Q9BPY8
    Pathways
    Regulation of Muscle Cell Differentiation
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