TCN2 antibody

Catalog No. ABIN1387225

Product Details anti-TCN2 Antibody

Target: TCN2 (Transcobalamin II (TCN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TCN2/Transcobalamin II

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TCN2

Target: TCN2 (Transcobalamin II (TCN2))

Alternative Name: TCN2 (TCN2 Products)

Synonyms: AW208754 antibody, Tcn-2 antibody, Tc2 antibody, Tcn2p antibody, D22S676 antibody, D22S750 antibody, II antibody, TC antibody, TC II antibody, TC-2 antibody, TC2 antibody, TCII antibody, transcobalamin 2 antibody, Tcn2 antibody, TCN2 antibody

Background:

Synonyms: Macrocytic anemia, TC, TC II, TC-2, TC2, TCII, TCN 2, TCO2_HUMAN, Transcobalamin 2, Transcobalamin II, Transcobalamin II, macrocytic anemia, Transcobalamin-2, Vitamin B12 binding protein 2.

Background: Transcobalamin I (TCI) and Transcobalamin II (TCII) are secreted proteins belonging to the eukaryotic cobalamin transport proteins family and also to the vitamin B12-binding protein family. The genes encoding these proteins map to chromosome 11q11-q12 and 22q12.2, respectively. Transcobalamin I is a constituent of secondary granules in neutrophils, while Transcobalamin II binds cobalamin and mediates its transport into cells. These plasma proteins are expressed in various tissues and secretions.

Gene ID: 6948