WIPF2 antibody

Catalog No. ABIN1387209

Product Details anti-WIPF2 Antibody

Target: WIPF2 (WAS/WASL Interacting Protein Family, Member 2 (WIPF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WIPF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human WIPF2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for WIPF2

Target: WIPF2 (WAS/WASL Interacting Protein Family, Member 2 (WIPF2))

Alternative Name: WIPF2 (WIPF2 Products)

Synonyms: wich antibody, wire antibody, MGC86383 antibody, wip/cr16 antibody, WICH antibody, WIRE antibody, 1110014J05Rik antibody, 5730509C05Rik antibody, AA407487 antibody, Gm1176 antibody, Wich antibody, Wire antibody, RGD1561080 antibody, WAS/WASL interacting protein family member 2 antibody, WAS/WASL interacting protein family member 2 S homeolog antibody, WAS/WASL interacting protein family, member 2 antibody, WIPF2 antibody, wipf2.S antibody, Wipf2 antibody

Background:

Synonyms: WAS/WASL interacting protein family member 2, WASP binding protein, WASP interacting protein related protein, WICH, WIP and CR16 homologous protein, WIP related protein, WIPF 2, WIR, WIPF2_HUMAN.

Background: WIRE, also known as WIPF2 (WAS/WASL interacting protein family, member 2) or WICH, is a 440 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one WH2 domain. Expressed ubiquitously with highest expression in colon, brain, lung and stomach, WIRE functions as an N-WASP-interacting protein that plays an important role in the organization and mobilization of the Actin cytoskeleton. Additionally, WIRE is involved in the formation of cell surface protrusions and may also provide a link between the cytoskeletal machinery and PDGF-B receptors. Multiple alternatively spliced isoforms of WIRE exist and are encoded by a gene that maps to human chromosome 17.

Gene ID: 147179