BAALC antibody

Catalog No. ABIN1387199

Product Details anti-BAALC Antibody

Target: BAALC (Brain and Acute Leukemia, Cytoplasmic (BAALC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAALC antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BAALC

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BAALC

Target: BAALC (Brain and Acute Leukemia, Cytoplasmic (BAALC))

Alternative Name: BAALC (BAALC Products)

Synonyms: si:zc215i13.3 antibody, si:ch211-215i13.3 antibody, BAALC antibody, 2810457D07Rik antibody, BAALC, MAP3K1 and KLF4 binding antibody, brain and acute leukemia, cytoplasmic antibody, BAALC antibody, baalc antibody, Baalc antibody

Background:

Synonyms: BAALC, BAALC_HUMAN, Brain and acute leukemia cytoplasmic, Brain and acute leukemia cytoplasmic protein, brain and acute leukemia, cytoplasmic, FLJ12015.

Background: BAALC is a 180 amino acid protein that localizes to both the membrane and the cytoplasm and exists as multiple alternatively spliced isoforms. Expressed by hematopoetic and neural cells, BAALC interacts with CaMKII and is thought to play a role in synaptic function at postsynaptic lipid rafts. BAALC may be overexpressed in acute myeloid leukemia (AML), suggesting a role in tumorigenesis. The gene encoding BAALC maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8.

Gene ID: 79870