C1orf144 antibody

Catalog No. ABIN1387177

Product Details anti-C1orf144 Antibody

Target: C1orf144 (Chromosome 1 Open Reading Frame 144 (C1orf144))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1orf144 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf144

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C1orf144

Target: C1orf144 (Chromosome 1 Open Reading Frame 144 (C1orf144))

Alternative Name: C1orf144 (C1orf144 Products)

Synonyms: MGC82291 antibody, MGC76116 antibody, DKFZp468H135 antibody, C1orf144 antibody, SZRD1 antibody, 1110022I03 antibody, D4Ertd22e antibody, C2H1orf144 antibody, wu:fb15h05 antibody, wu:fk86c07 antibody, zgc:109926 antibody, RGD1560286 antibody, SUZ RNA binding domain containing 1 L homeolog antibody, SUZ RNA binding domain containing 1 antibody, szrd1.L antibody, szrd1 antibody, SZRD1 antibody, Szrd1 antibody

Background:

Synonyms: DKFZp566C0424, MGC70432, Putative MAPK-activating protein PM18/PM20/PM22, UPF0485 protein C1orf144, SZRD1_HUMAN, SUZ domain-containing protein 1.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf144 gene product has been provisionally designated C1orf144 pending further characterization.

Gene ID: 26099