DNAH14 antibody

Catalog No. ABIN1387169

Product Details anti-DNAH14 Antibody

Target: DNAH14 (Dynein, Axonemal, Heavy Chain 14 (DNAH14))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAH14 antibody is un-conjugated

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf67/DNAH14

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DNAH14

Target: DNAH14 (Dynein, Axonemal, Heavy Chain 14 (DNAH14))

Alternative Name: C1orf67 (DNAH14 Products)

Synonyms: C1orf67 antibody, Dnahc14 antibody, HL-18 antibody, HL18 antibody, dynein axonemal heavy chain 14 antibody, DNAH14 antibody

Background:

Synonyms: Chromosome 1 open reading frame 67, Coiled coil domain containing protein C1orf67, Hypothetical protein LOC200095, MGC149665, MGC149666, MGC27277, MGC51214, DYH14_HUMAN.

Background: Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors, the complex transports cellular cargos towards the central region of the cell. Axonemal dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. DNAH14 (dynein, axonemal, heavy chain 14), also known as C1orf67 or HL18, is a 3,507 amino acid member of the dynein heavy chain protein family. DNAH14 is one of the force generating protein of respiratory cilia and may be involved in sperm motility through sperm flagellar assembly.

Gene ID: 127602