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TSEN15 antibody

TSEN15 Reactivity: Human, Mouse, Rat WB, IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387164
  • Target See all TSEN15 Antibodies
    TSEN15 (tRNA Splicing Endonuclease 15 Homolog (TSEN15))
    Reactivity
    • 17
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 14
    • 3
    Rabbit
    Clonality
    • 15
    • 2
    Polyclonal
    Conjugate
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TSEN15 antibody is un-conjugated
    Application
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C1orf19/SEN15
    Isotype
    IgG
    Top Product
    Discover our top product TSEN15 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    TSEN15 (tRNA Splicing Endonuclease 15 Homolog (TSEN15))
    Alternative Name
    C1orf19 (TSEN15 Products)
    Synonyms
    5730449L18Rik antibody, AL023077 antibody, Sen15 antibody, C1orf19 antibody, sen15 antibody, tRNA splicing endonuclease subunit 15 antibody, Tsen15 antibody, TSEN15 antibody
    Background

    Synonyms: Chromosome 1 open reading frame 19, Chromosome 1 open reading frame 19, isoform CRA_c, HsSen15, sen15, SEN15 homolog, SEN15_HUMAN, tRNA intron endonuclease Sen15, tRNA splicing endonuclease 15 homolog S. cerevisiae, tRNA splicing endonuclease subunit Sen15, tRNA-intron endonuclease SEN15, tRNA-splicing endonuclease subunit SEN15, Tsen15.

    Background: SEN15, also known as TSEN15 (tRNA-splicing endonuclease subunit Sen15) or C1orf19, is a nuclear protein that plays a role in tRNA splicing. Widely expressed with highest expression in testis and uterus, SEN15 is a non-catalytic subunit of the multi-protein tRNA-splicing endonuclease complex. The endonuclease complex is responsible for identifying and cleaving pre-tRNA at both 5? and 3? splice sites, thereby releasing introns and free tRNA molecules with 2',3' cyclic phosphates and 5'-OH termini. In addition to its role in pre-tRNA splicing, the endonuclease complex participates in mRNA processing and, via its association with pre-mRNA processing factors, is thought to link pre-tRNA and pre-mRNA splicing events. As a subunit of the complex, SEN15 participates in protein expression and, ultimately, cell growth and division.

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