C10orf27 antibody (AA 70-120)

Catalog No. ABIN1387128

Product Details anti-C10orf27 Antibody

Target: C10orf27 (Chromosome 10 Open Reading Frame 27 (C10orf27))

Binding Specificity: AA 70-120

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C10orf27 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C10orf27/SPATIAL

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C10orf27

Target: C10orf27 (Chromosome 10 Open Reading Frame 27 (C10orf27))

Alternative Name: C10orf27 (C10orf27 Products)

Synonyms: C28H10orf27 antibody, SPATIAL antibody, C10orf27 antibody, spatial antibody, 1700021K02Rik antibody, AI428928 antibody, Spatial antibody, Titest antibody, thymus, brain and testes associated antibody, TBATA antibody, Tbata antibody

Background:

Synonyms: C10orf27, chromosome 10 open reading frame 27, FLJ32820, Stromal protein associated with thymii and lymph node homolog, stromal protein associated with thymii and lymph nodes, TBATA_HUMAN, SPATIAL, TBATA, thymus, brain and testes associated

Background: C10orf27, also known as spatial, is a 351 amino acid cytoplasmic protein belonging to the spatial family. C10orf27 is suggested to play a role in spermatid differentiation. Existing as two alternatively spliced isoforms, C10orf27 is widely expressed in multiple tissues, including brain, thymus and testis. C10orf27 may be associated with multiple sclerosis (MS) susceptibility and pathogenesis. MS is an inflammatory disease that causes gradual destruction of myelin in the central nervous system. C10orf27 is encoded by a gene located on human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5 % of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.

Gene ID: 219793

UniProt: Q96M53