PSMD7 antibody

Catalog No. ABIN1387053

Product Details anti-PSMD7 Antibody

Target: PSMD7 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7 (PSMD7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PSMD7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PSMD7

Target: PSMD7 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7 (PSMD7))

Alternative Name: PSMD7 (PSMD7 Products)

Synonyms: wu:fi03c01 antibody, zgc:55284 antibody, CG3416 antibody, Dmel\\CG3416 antibody, PRSC_DROME antibody, RPN8 antibody, Rpn8 antibody, S12 antibody, l(2)k08003 antibody, p39B antibody, DDBDRAFT_0205949 antibody, DDBDRAFT_0232987 antibody, DDB_0205949 antibody, DDB_0232987 antibody, MOV34 antibody, P40 antibody, AW107203 antibody, Mov-34 antibody, Mov34 antibody, proteasome 26S subunit, non-ATPase 7 antibody, Regulatory particle non-ATPase 8 antibody, 26s proteasome regulatory subunit s12 antibody, 26S proteasome non-ATPase regulatory subunit 7 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 antibody, psmd7 antibody, Rpn8 antibody, PSMD7 antibody, PY05051 antibody, psmD7 antibody, Psmd7 antibody

Background:

Synonyms: 26S proteasome non ATPase regulatory subunit 7, 26S proteasome non-ATPase regulatory subunit 7, 26S proteasome regulatory subunit rpn8, 26S proteasome regulatory subunit S12, Moloney leukemia virus 34 proviral integration, MOV 34, MOV 34L, MOV34, Mov34 homolog, Mov34 protein homolog, MOV34L, P40 antibody Proteasome prosome macropain 26S subunit non ATPase 7, Proteasome 26S non ATPase subunit 7, Proteasome 26S S12, Proteasome subunit p40, PSD7_HUMAN, PSMD 7, PSMD-7, PSMD7, S12 antibody.

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.

Gene ID: 5713

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway