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MARCH3 antibody

MARCH3 Reactivity: Human, Mouse, Rat WB, IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387033
  • Target See all MARCH3 Antibodies
    MARCH3 (Membrane-Associated Ring Finger (C3HC4) 3, E3 Ubiquitin Protein Ligase (MARCH3))
    Reactivity
    • 44
    • 26
    • 24
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 41
    • 3
    Rabbit
    Clonality
    • 42
    • 2
    Polyclonal
    Conjugate
    • 16
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MARCH3 antibody is un-conjugated
    Application
    • 42
    • 21
    • 12
    • 5
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MARCH3
    Isotype
    IgG
    Top Product
    Discover our top product MARCH3 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    MARCH3 (Membrane-Associated Ring Finger (C3HC4) 3, E3 Ubiquitin Protein Ligase (MARCH3))
    Alternative Name
    MARCH3 (MARCH3 Products)
    Synonyms
    6330411I15Rik antibody, A530081L18Rik antibody, AI843639 antibody, MARCH-III antibody, RNF173 antibody, membrane-associated ring finger (C3HC4) 3 antibody, membrane associated ring-CH-type finger 3 antibody, March3 antibody, MARCH3 antibody
    Background

    Synonyms: E3 ubiquitin-protein ligase MARCH3, FLJ20096, MARCH-III, March3, MARH3_HUMAN, Membrane associated ring finger C3HC4 3, Membrane-associated RING finger protein 3, Membrane-associated RING-CH protein III, RING finger protein 173, RNF173.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH3 (membrane-associated ring finger (C3HC4) 3), also known as RNF173, is a 253 amino acid multi-pass membrane protein that localizes to cytoplasmic vesicles and early endosomes and contains one RING-CH-type zinc finger. Involved in the pathway of protein modification, MARCH3 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to be involved in endosomal trafficking events.

    Gene ID
    115123
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