LRCH3 antibody

Catalog No. ABIN1387026

Product Details anti-LRCH3 Antibody

Target: LRCH3 (Leucine-Rich Repeats and Calponin Homology (CH) Domain Containing 3 (LRCH3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRCH3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRCH3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for LRCH3

Target: LRCH3 (Leucine-Rich Repeats and Calponin Homology (CH) Domain Containing 3 (LRCH3))

Alternative Name: LRCH3 (LRCH3 Products)

Synonyms: 2210409B11Rik antibody, AW215594 antibody, Gm1742 antibody, leucine rich repeats and calponin homology domain containing 3 antibody, leucine-rich repeats and calponin homology (CH) domain containing 3 antibody, Lrch3 antibody, LRCH3 antibody

Background:

Synonyms: Leucine rich repeats and calponin homology CH domain containing 3, LRCH3, MGC4126, LRCH3_HUMAN.

Background: Members of the leucine-rich repeat family includes LRCH1, LRCH2, LRCH3 and LRCH4. All family members contain one calponin-homology domain and nine leucine-rich repeats. The best characterized leucine-rich repeat family member is LRCH4, which is suggested to be involved in ligand binding in the brain, with expression observed primarily in the hippocampus. As a cell adhesion molecule and signal receptor, LRCH4 may play an important role in maintenance of hippocampus-dependent memories, with defects in the gene possibly contributing to a loss of long-term memory. The gene encoding LRCH3 maps to human chromosome 3, which spans 200 million base pairs and encodes between 1,100 and 1,500 genes. There are three isoforms of LRCH3 that are produced as a result of alternative splicing events.

Gene ID: 84859